09/28/2018 / By RJ Jhonson
Like a lot of other fruits, pomegranate (Punica granatum), is great for more than just your sweet fix. A study published in the journal BMC Complementary and Alternative Medicine discusses its ability to soothe muscle spasms, particularly, the smooth muscles, indicating its potential as a treatment for spasm-related conditions like diarrhea.
Past research has confirmed the spasmolytic properties – the ability to reduce or cease spasms – of pomegranate rind, but the exact mechanism was not made clear. The authors of the research, therefore, performed an in vitro study that examined the rind’s therapeutic effects.
They collected pomegranate rind extracts (Pg. Cr.) which they tested on rabbit’s jejunal preparations. The isolated jejunum – a part of the small intestine – of a rabbit can be kept alive after the animal has died, making it ideal for in vitro tests on smooth muscles, which line organs like the heart and the intestines.
Pg. Cr. was tested on the jejunal preparation in varying doses, as well as contractions induced by barium chloride and potassium chloride (KCl). The researchers observed that contrary to previous findings, Pg. Cr. actually possessed spasmogenic properties – it caused spasms. Further investigation revealed this effect to be the result of histaminergic and cholinergic receptors in the intestine. Interestingly, increasing the dose of Pg. Cr. manifested the intended spasmolytic effect.
The researchers used a mouse model to determine the toxicity of Pg. Cr. They found that the extract remained safe up to a dosage of 100 mg/kg. A dosage on and above 1,000 mg/kg could be harmful.
Phytochemical screening indicated the presence of saponins, tannins, carbohydrates, proteins, flavonoids, saponins and steroids. Alkaloids and triterpenoids were not found. (Related: No more oopsy daisies: Taking a probiotic drink can prevent diarrhea.)
Spasms in the stomach are among of the most common types of smooth muscle spasms. It may occur because of several factors, such as:
The best way to treat a spasm is to determine its cause first. Depending on the gravity of the situation, you may need to visit a health professional right away. For light cases, you may find relief in home remedies.
Find other remedies for muscle spasms at Remedies.news.
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Tagged Under: food as medicine, intestinal spasms, natural treatment, pomegranate, Punica granatum, smooth muscle spasms, spasms, stomach spasms